From Wikipedia:
In the early 1990s, many educational games were released in the Mario series of video games, including Mario is Missing!, a geography-based game for the PC, Macintosh, Super NES and NES, I Am a Teacher: Super Mario Sweater, a Famicom Disk System game released in 1988, Two Mario Teaches Typing games, Three Mario's Early Years games, Mario's Time Machine, similar to Mario is Missing, and Super Mario Bros. Learn about Mario Is Missing!